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The Nikkei 225 index closed at 39,881.10 points in early trading, up 1.29%.Runhe Software and other 300 million yuan set up a venture capital fund partnership. The enterprise search APP shows that Yuanshi (Changzhou) venture capital fund partnership (limited partnership) was established recently with a capital contribution of 300 million yuan, and its business scope includes: venture capital (limited investment in unlisted enterprises); Engage in equity investment, investment management, asset management and other activities with private equity funds. Enterprise equity penetration shows that the enterprise is jointly held by Runhe Software.The next "explosion point" of biomedicine may appear in Shenzhen. "China's pharmaceutical innovation ranks first in the second echelon in the world in terms of the quantitative indicators of R&D pipelines and listed new drugs." A few days ago, Song Ruilin, executive president of China Pharmaceutical Innovation Promotion Association, held the "Star of the Bay Area" biomedical source innovation conference in Shenzhen, and believed that China's pharmaceutical research and industrial development were entering a new stage of innovation. Chen Qiyu, vice president of China Pharmaceutical Innovation Promotion Association and executive director and co-CEO of Fosun International, said that Shenzhen has great advantages and development momentum in linking Greater Bay Area's urban development and AI technology. By leveraging the resources in the Bay Area and making good use of these advantages, it is possible to find a new fulcrum in the future biomedical R&D innovation track, and the next "explosion point" of biomedicine is likely to appear in Shenzhen.

The turnover of Shanghai and Shenzhen stock markets exceeded 1 trillion for the 52nd consecutive trading day, exceeding 10 billion compared with yesterday.Ministry of Water Resources: A number of projects to fully promote the construction of the national water network are accelerating. On December 12, the State Council Office held a press conference to introduce the tenth anniversary of the first phase of the East Middle Route of the South-to-North Water Transfer Project. Zhang Xiangwei, director of the Planning Department of the Ministry of Water Resources, said that the Ministry of Water Resources has made every effort to promote the construction of the national water network according to the overall deployment of the Outline of the National Water Network Construction Plan, focusing on networking, supplementing the network and strengthening the chain. Judging from the main artery of the national water network, the middle route of South-to-North Water Transfer Project is accelerating. From the point of view of the backbone water transport and drainage channels of the national water network, a number of major inter-basin water diversion projects have been completed, such as connecting the Yangtze River and Huaihe River, connecting the Han River and Weihe River, and allocating water resources in the Pearl River Delta. At the same time, the water resources allocation around the Beibu Gulf, the backbone project of Jilin water network, the second phase of Huaihe River's waterway into the sea and other projects that have been demonstrated for many years have all started construction and are actively promoting the implementation of the projects.The South-to-North Water Transfer Project has transferred 76.7 billion cubic meters of water to support the GDP growth of more than 16 trillion yuan in the northern region. The State Council held a press conference to introduce the tenth anniversary of the first phase of the South-to-North Water Transfer Project. Wang Daoxi, Vice Minister of the Ministry of Water Resources, said that the project has transformed the water resources advantage in the southern region into the development advantage in the northern region. Up to today, the South-to-North Water Transfer Project has transferred 76.7 billion cubic meters of water, supporting the GDP growth of more than 16 trillion yuan in the northern region.

Tsinghua University National Key Laboratory Base was established in Changping National Heavy Base at the end of the first phase. At present, Changping District is cooperating with Tsinghua University to build Tsinghua Nankou National Heavy Base, revitalizing the industrial remains of the "three major factories" in Nankou Town through urban renewal, and undertaking more than 14 national key laboratories in Tsinghua University. It is expected to be put into use in 2025, which will be the largest and most concentrated national key laboratory research base outside the main campus of Tsinghua University. Among them, two laboratories, Intelligent Green Vehicle and Transportation and New Power Operation and Control, will be completed and unveiled at the end of December this year. (Beijing Daily)By 11:30, 100 stocks in the two cities had daily limit.Shanghai Nickel's main contract has expanded, and now it has risen by more than 3% to 129,170 yuan/ton.